113 research outputs found

    Implementación y configuración de una red lan para mejorar la conectividad en el laboratorio de desarrollo de software de la Universidad Técnica de Cotopaxi extensión La Maná periodo octubre 2014 – febrero 2015

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    The present research work originates within the Technical University of Cotopaxi in the Laboratory of Software Development because this does not count with a LAN network that enables them to develop the functions and tasks properly, this is due because currently the computing resources and the way in which data are reported have gained a great current importance within all fields of study, the speed and the way that data is transmitted to expedite the development of processes and operations; in the development of the project was used for the analysis and interpretation of the results was used an analytical methodology the same that allowed to establish the theoretical foundations that served Support for research, similarly used a field research, which helped to obtain information on the activities performed in the laboratory with the purpose of establishing the qualities that must have the LAN....El presente trabajo de investigación se origina dentro de la Universidad Técnica de Cotopaxi en el Laboratorio de Desarrollo de Software debido a que este no cuenta con un red LAN que les permita desarrollar las funciones y tareas adecuadamente, esto se debe que en la actualidad los recursos informáticos y la forma en que se comunican los datos han cobrado una gran importancia dentro de todos los campos de estudio, la velocidad y la forma que se transmiten los datos ayudara en el desarrollo de procesos y operaciones.; en el desarrollo del proyecto se utilizó el análisis y la interpretación de los resultados se empleó una metodología analítica la misma que permitió establecer los fundamentos teóricos que sirvieron de respaldo para la investigación, de igual forma se empleó una investigación de campo, la cual se utilizó para obtener información sobre las actividades que se realizan en el laboratorio con el fin de establecer las cualidades que debe tener la red LAN...

    Statistics of injected power on a bouncing ball subjected to a randomly vibrating piston

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    International audienceWe present an experimental study on the statistical properties of the injected power needed to maintain an inelastic ball bouncing constantly on a randomly accelerating piston in the presence of gravity. We compute the injected power at each collision of the ball with the moving piston by measuring the velocity of the piston and the force exerted on the piston by the ball. The probability density function of the injected power has its most probable value close to zero and displays two asymmetric exponential tails, depending on the restitution coefficient, the piston acceleration, and its frequency content. This distribution can be deduced from a simple model assuming quasi-Gaussian statistics for the force and velocity of the piston

    Improved image quality in pinhole SPECT by accurate modeling of the point spread function in low magnification systems

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    PURPOSE: Single photon emission computed tomography (SPECT) has become an important noninvasive imaging technique in small-animal research. Due to the high resolution required in small-animal SPECT systems, the spatially variant system response needs to be included in the reconstruction algorithm. Accurate modeling of the system response should result in a major improvement in the quality of reconstructed images. The aim of this study was to quantitatively assess the impact that an accurate modeling of spatially variant collimator/detector response has on image-quality parameters, using a low magnification SPECT system equipped with a pinhole collimator and a small gamma camera. METHODS: Three methods were used to model the point spread function (PSF). For the first, only the geometrical pinhole aperture was included in the PSF. For the second, the septal penetration through the pinhole collimator was added. In the third method, the measured intrinsic detector response was incorporated. Tomographic spatial resolution was evaluated and contrast, recovery coefficients, contrast-to-noise ratio, and noise were quantified using a custom-built NEMA NU 4-2008 image-quality phantom. RESULTS: A high correlation was found between the experimental data corresponding to intrinsic detector response and the fitted values obtained by means of an asymmetric Gaussian distribution. For all PSF models, resolution improved as the distance from the point source to the center of the field of view increased and when the acquisition radius diminished. An improvement of resolution was observed after a minimum of five iterations when the PSF modeling included more corrections. Contrast, recovery coefficients, and contrast-to-noise ratio were better for the same level of noise in the image when more accurate models were included. Ring-type artifacts were observed when the number of iterations exceeded 12. CONCLUSIONS: Accurate modeling of the PSF improves resolution, contrast, and recovery coefficients in the reconstructed images. To avoid the appearance of ring-type artifacts, the number of iterations should be limited. In low magnification systems, the intrinsic detector PSF plays a major role in improvement of the image-quality parameters.Gobierno de EspañaCDTI-CENIT (AMIT project)Instituto de Salud Carlos III (ISCIII

    Role of the basin boundary conditions in gravity wave turbulence

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    Gravity wave turbulence is studied experimentally in a large wave basin where irregular waves are generated unidirectionally. The role of the basin boundary conditions (absorbing or reflecting) and of the forcing properties are investigated. To that purpose, an absorbing sloping beach opposite to the wavemaker can be replaced by a reflecting vertical wall. We observe that the wave field properties depend strongly on these boundary conditions. Quasi-one dimensional field of nonlinear waves propagate before to be damped by the beach whereas a more multidirectional wave field is observed with the wall. In both cases, the wave spectrum scales as a frequency-power law with an exponent that increases continuously with the forcing amplitude up to a value close to -4, which is the value predicted by the weak turbulence theory. The physical mechanisms involved are probably different according to the boundary condition used, but cannot be easily discriminated with only temporal measurements. We have also studied freely decaying gravity wave turbulence in the closed basin. No self-similar decay of the spectrum is observed, whereas its Fourier modes decay first as a time power law due to nonlinear mechanisms, and then exponentially due to linear viscous damping. We estimate the linear, nonlinear and dissipative time scales to test the time scale separation that highlights the important role of a large scale Fourier mode. By estimation of the mean energy flux from the initial decay of wave energy, the Kolmogorov-Zakharov constant is evaluated and found to be compatible with a recent theoretical value.Comment: Journal of Fluid Mechanics, Cambridge University Press (CUP), 2015, in press in JF

    Restauraciones estéticas en túnel

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    Las restauraciones de lesiones de caries proximales mediante el uso de preparaciones en túnel tienen como finalidad conservar tejido dentario, fundamentalmente el reborde marginal para mantener la resistencia estructural de la pieza dentaria en cuestión. Albers (2002) informa que originalmente las tunelizaciones fueron propuestas para inocular flúor a las áreas proximales de primeros molares, por intermedio de restauraciones que lo liberaran realizadas en los segundos molares temporarios. A estos se los abordaba desde oclusal con dirección oblicua hacia proximal respetando el reborde marginal, y se los obturaba con cemento de silicato. Posteriormente se fue perfeccionando la técnica y se la difundió para solucionar procesos cariosos menores en proximal de premolares y molares, con la sugerencia de realizar las obturaciones con ionómero vítreo y recubierto en oclusal con resina compuesta (Hunt, 1984; Knight, 1984). Sin embargo, por conservadora de las estructuras naturales, también pueden ser la alternativa restauradora más conveniente para otras situaciones más complejas.Categoría: Casos clínicos.Facultad de Odontologí

    Integration of advanced 3D SPECT modeling into the open-source STIR framework

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    Purpose: The Software for Tomographic Image Reconstruction (STIR,http://stir.sourceforge.net) package is an open source object-oriented library implemented in C++. Although its modular design is suitable for reconstructing data from several modalities, it currently only supports Positron Emission Tomography (PET) data. In this work, the authors present results for Single Photon Emission Computed Tomography (SPECT) imaging. / Methods: This was achieved by the complete integration of a 3D SPECT system matrix modeling library into STIR. / Results: The authors demonstrate the flexibility of the combined software by reconstructing simulated and acquired projections from three different scanners with different iterative algorithms of STIR. / Conclusions: The extension of the open source STIR project with advanced SPECT modeling will enable the research community to study the performance of several algorithms on SPECT data, and potentially implement new algorithms by expanding the existing framework

    Metabolic effects of darunavir/ritonavir versus atazanavir/ritonavir in treatment-naive, HIV Type 1-infected subjects over 48 weeks

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    We assessed metabolic changes for darunavir/ritonavir (DRV/r) once daily (qd) versus atazanavir/ritonavir (ATV/r) qd with fixed-dose tenofovir/emtricitabine. This was a phase 4, multicenter, open-label, randomized exploratory study. Treatment-naive, HIV-1-infected adults received DRV/r 800/100 mg qd or ATV/r 300/100 mg qd, both with emtricitabine/tenofovir 200/300 mg qd. Primary end point: change in triglyceride levels from baseline to week 12. Secondary end points: week 12 and week 48 changes in lipid parameters, insulin sensitivity, inflammatory/coagulation/bacterial translocation biomarkers, viral load, CD4(+) cell count, and week 48 changes in adipose tissue distribution and subjects' perceptions of body changes. In the DRV/r arm, 32/34 and 29/34 subjects completed weeks 12 and 48, respectively; in the ATV/r arm, 30/31 and 25/31 subjects completed weeks 12 and 48, respectively. Small changes in lipid parameters from baseline to weeks 12 and 48 were observed in both arms. Differences were noted between arms in mean changes in total cholesterol (DRV/r, 20.3 mg/dl; ATV/r, 4.6 mg/dl) and apolipoprotein A1 (DRV/r, 10.7 mg/dl; ATV/r, –0.7 mg/dl) at week 12. At week 48, no clinically relevant differences between arms were noted for changes in any lipid parameter, fasting glucose, or insulin sensitivity. Biomarkers generally decreased and efficacy parameters improved in both arms over 48 weeks. Changes in adipose tissue were small and comparable between arms. Subjects' perceptions of body changes generally improved in both study arms. This first pilot comparison in HIV-1-infected subjects suggests that DRV/r has a metabolic profile similar to ATV/r over 48 weeks of treatment. Further randomized studies are warranted

    Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model

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    Characterization of a pandemic 2009 H1N1 influenza virus isolated from a fatal case patient (F-IAV), showed the presence of three different mutations; potential determinants of its high pathogenicity that were located in the polymerase subunits (PB2 A221T and PA D529N) and the hemagglutinin (HA S110L). Recombinant viruses containing individually or in combination the polymerase mutations in the backbone of A/California/04/09 (CAL) showed that PA D529N was clearly involved in the increased pathogenicity of the F-IAV virus. Here, we have evaluated the contribution of HA S110L to F-IAV pathogenicity, through introduction of this point mutation in CAL recombinant virus (HA mut). The HA S110L protein has similar pH stability, comparable mobility, and entry properties both in human and mouse cultured cells that wild type HA. The change HA S110L leads to a non-significant trend to reduce the replication capacity of influenza virus in tissue culture, and HA mut is better neutralized than CAL virus by monoclonal and polyclonal antibodies against HA from CAL strain. In addition, recombinant viruses containing HA S110L alone or in combination with polymerase mutations considerably increased the LD50 in infected mice. Characterization of the lungs of HA mut infected animals showed reduced lung damage and inflammation compared with CAL infected mice. Accordingly, lower virus replication, decreased presence in bronchioli and parenchyma and lower leukocytes and epithelial infected cells were found in the lungs of HA mut-infected animals. Our results indicate that, mutation HA S110L constitutes a determinant of attenuation and suggest that its interaction with components of the respiratory tract mucus and lectins, that play an important role on influenza virus outcome, may constitute a physical barrier impeding the infection of the target cells, thus compromising the infection outcome

    Perfil social de la población atendida en la asignatura Operatoria Dental “A” durante un cuatrimestre

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    Esta asignatura, Operatoria Dental, tiene un rol relevante en la atención de los pacientes que concurren a la Facultad de Odontología, ya que en ella se restauran las piezas dentarias cuya morfología ha sufrido deterioro y pérdida de sustancia, como consecuencia de la enfermedad prevalente en la cavidad bucal, es decir la caries dental básicamente, además de otros trastornos como la pérdida de tejidos dentarios de origen accidental, por enfermedades de origen psicosomático, etc., motivos éstos que traen aparejadas consecuencias de carácter funcional y estéticos de gran importancia en nuestra población. Por este motivo nuestra Asignatura recepta una gran cantidad de pacientes, que a través de un simple instrumento como es la ficha de su estado buco dental, más un pormenorizado interrogatorio, posibilita dejar asentado en una historia clínica sus datos personales y su estado de salud general, pudiendo hacerse un estudio pormenorizado de las necesidades de esta población y al mismo tiempo nos permite realizar una evaluación de sus principales dolencias.Facultad de Odontologí
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